Cannabinoid Receptor
Cannabinoid Receptor
Cannabinoid receptors are currently classified into three groups: central (CB1), peripheral (CB2) and GPR55, all of which are G-protein-coupled. CB1 receptors are primarily located at central and peripheral nerve terminals. CB2 receptors are predominantly expressed in non-neuronal tissues, particularly immune cells, where they modulate cytokine release and cell migration. Recent reports have suggested that CB2 receptors may also be expressed in the CNS. GPR55 receptors are non-CB1/CB2 receptors that exhibit affinity for endogenous, plant and synthetic cannabinoids. Endogenous ligands for cannabinoid receptors have been discovered, including anandamide and 2-arachidonylglycerol.
Cannabinoid Receptor Isoform Specific Products
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Cannabinoid Receptor Inhibitors
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Cannabinoid Receptor Agonists
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Cannabinoid Receptor Antagonists
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Cannabinoid Receptor Activators
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Cannabinoid Receptor Modulators
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Cannabinoid Receptor Chemical
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Cannabinoid Receptor Inducer
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Cannabinoid Receptor Degrader
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Cannabinoid Receptor Controls
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Cannabinoid Receptor Ligands
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Cannabinoid Receptor Related Products (448)
Related Products (448)
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Antibodies (1)
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Cannabinoid Receptor Isoform Comparison
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(-)-7-Nor-7-carboxy cannabidiol
0 ImagesCat. No.: HY-172080CAS No.: 63958-77-0(-)-7-Nor-7-carboxy cannabidiol is a phytocannabinoid metabolite. (-)-7-Nor-7-carboxy cannabidiol is a metabolite of Cannabidiol.
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CB2 receptor agonist 3 (Standard)
0 ImagesSynonyms: GP2a (Standard)CB2 receptor agonist 3 (Standard) is the analytical standard of CB2 receptor agonist 3 (HY-107471). This product is intended for research and analytical applications. CB2 receptor agonist 3 is a robust and selective CB2 cannabinoid agonist with Kis of 7.6 and 900 nM for CB2 and CB1, respectively. CB2 receptor agonist 3 significantly increases P-ERK 1/2 expression in HL-60 cells.
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Cannabinol methyl ether
0 ImagesCat. No.: HY-134038CAS No.: 41935-92-6Cannabinol methyl ether is a phytocannabinoid.
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Cannabigerovarin
0 ImagesCat. No.: HY-116661CAS No.: 55824-11-8Synonyms: CBGVCannabigerovarin (CRM) (Item No. 29117) is a certified reference material categorized as a phytocannabinoid.1 This product is intended for research and forensic applications.
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PTI-1
0 ImagesCat. No.: HY-129821CAS No.: 1400742-46-2PTI-1 is a synthetic cannabinoid (CB) that contains the 1-pentyl-indole structure.
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GW405833 hydrochloride (Standard)
0 ImagesCat. No.: HY-110036ARCAS No.: 1202865-22-2Synonyms: L768242 hydrochloride (Standard)GW405833 hydrochloride (Standard) is the analytical standard of GW405833 (hydrochloride) (HY-110036A). This product is intended for research and analytical applications. GW405833 (L768242) hydrochloride is a potent, selective cannabinoid receptor 2 (CB2) agonist. GW405833 has EC50 and Ki values of 0.65 nM and 3.92 nM for CB2, and EC50 and Ki values of 16.1 μM and 4772 nM for CB1. GW405833 hydrochloride also exhibits non-competitive CB1 antagonist, exerting its analgesic effect through a CB1 receptor (rather than CB2) dependent mechanism. GW405833 hydrochloride can significantly inhibit the production of cAMP stimulated by Forskolin (HY-15371). GW405833 hydrochloride inhibits glycolysis by down-regulating HIF-1α, thereby alleviating acute liver failure (ALF).
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Δ8-THCB
0 ImagesCat. No.: HY-170476CAS No.: 51768-59-3Synonyms: ∆8-TetrahydrocannabutolΔ8-THCB (∆8-Tetrahydrocannabutol) is a structural analog of phytocannabinoids. Δ8-THCB is also an analog of Δ8-tetrahydrocannabinol.
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Δ8-Tetrahydrocannabivarin
0 ImagesCat. No.: HY-137543CAS No.: 31262-38-1Δ8-Tetrahydrocannabivarin is a cannabinoid.
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11-Nor-9(S)-carboxy-hexahydrocannabinol
0 ImagesCat. No.: HY-170047ACAS No.: 64663-37-2Synonyms: 11-Nor-9α-carboxy-HHC11-Nor-9(S)-carboxy-hexahydrocannabinol (11-Nor-9α-carboxy-HHC) is structurally similar to known phytocannabinoids.
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AM251 (Standard)
0 ImagesAM251 (Standard) is the analytical standard of AM251. This product is intended for research and analytical applications. AM251 is a selective cannabinoid 1 (CB1) receptor antagonist with an IC50 of 8 nM. AM251 also acts as a potent GPR55 agonist with an EC50 of 39 nM.
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Tricosanoyl ethanolamide
0 ImagesCat. No.: HY-165082CAS No.: 171022-15-4Synonyms: N-(2-Hydroxyethyl)-tricosanamideTricosanoyl ethanolamide is a member of endocannabinoids and its structure consists of ethanolamine and tricosanoic acid, which contains 23 carbon atoms. Tricosanoyl ethanolamide can be used for research of diseases related to the endocannabinoid system.
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Cannabinol acetate
0 ImagesCat. No.: HY-170727CAS No.: 51895-51-3Synonyms: AcetylcannabinolCannabinol acetate (Acetylcannabinol) is structurally similar to known phytocannabinoids.
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Cannabinol ethyl
0 ImagesCat. No.: HY-171024CAS No.: 99623-70-8Synonyms: CBN-C2Cannabinol ethyl (CBN-C2) is structurally similar to known phytocannabinoids.
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GW 833972A (Standard)
0 ImagesCat. No.: HY-101765RCAS No.: 1092502-33-4GW 833972A (Standard) is the analytical standard of GW 833972A (HY-101765). This product is intended for research and analytical applications. GW 833972A is a selective CB₂ receptor agonist with pEC₅₀ of the human CB₂ receptor for GW 833972A of 7.3, and its selectivity for the CB₂ receptor is approximately 1000 times higher than that for the CB₁ receptor. GW 833972A inhibits induced neuronal depolarization and suppresses coughing caused by citric acid in guinea pig models. GW 833972A can be used for the study of chronic cough.
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8(S)-Hydroxy-9(S)-hexahydrocannabinol
0 ImagesCat. No.: HY-168790CAS No.: 36403-93-78(S)-Hydroxy-9(S)-hexahydrocannabinol is structurally similar to known phytocannabinoids.
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exo-THCP
0 ImagesCat. No.: HY-170695CAS No.: 2897582-92-0Synonyms: exo-Tetrahydrocannabiphorolexo-THCP (exo-Tetrahydrocannabiphorol) is structurally similar to known phytocannabinoids.
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Olivetol (Standard)
0 ImagesOlivetol (Standard) is the analytical standard of Olivetol. This product is intended for research and analytical applications. Olivetol is a naturally phenol found in lichens and produced by certain insects, acting as a competitive inhibitor of the cannabinoid receptors CB1 and CB2. Olivetol also inhibits CYP2C19 and CYP2D6 activity, with IC50s of 15.3 μM, 7.21 μM and Kis of 2.71 μM, 2.87 μM, respectively.
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(±)-6',7'-Dihydroxy cannabichromene
0 ImagesCat. No.: HY-170041CAS No.: 134840-96-3(±)-6',7'-Dihydroxy cannabichromene is a phytocannabinoid metabolite.
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5-Heptylresorcinol
0 ImagesCat. No.: HY-W195039CAS No.: 500-67-45-Heptylresorcinol is a precursor in the synthesis of cannabidiphorol.
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Cannabidivarin diacetate
0 ImagesCat. No.: HY-150348CAS No.: 2552800-24-3Cannabidivarin diacetateis structurally similar to known phytocannabinoids.
